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2021 Research Summary (PDF - click here)

Papers:

• Malîia M-D, Donos C, Barborica A, Popa I, Ciurea J, Cinatti S, Mîndruta I (2018): Functional mapping and effective connectivity of the human operculum. Cortex 109:303-321. https://doi.org/10.1016/j.cortex.2018.08.024 Available at: http://www.sciencedirect.com/science/article/pii/S0010945218302764
• Popa I, Barborica A, Scholly J, Donos C, Bartolomei F, Lagarde S, Hirsch E Valenti-Hirsch MP, Maliia MD, Arbune AA, Daneasa A, Ciurea J, Bajenaru OA, Mindruta I. Illusory own body perceptions mapped in the cingulate cortex—An intracranial stimulation study. Hum Brain Mapp. 2019;40:2813–26. https://doi.org/10.1002/hbm.24563.
• Arbune AA, Popa I, Mindruta I, Beniczky S, Donos C, Daneasa A, Malîia MD, Bajenaru OA, Ciurea J, Barborica A.  Sleep modulates effective connectivity: a study using intracranial stimulation and recording. Clin Neurophysiol. 2020 Feb;131(2):529-541. https://doi.org/10.1016/j.clinph.2019.09.010. Available at: https://www.sciencedirect.com/science/article/abs/pii/S1388245719312398
• Donos C, Mindruta I, Barborica A. Unsupervised Detection of High-Frequency Oscillations Using Time-Frequency Maps and Computer Vision. Front Neurosci. 2020 Mar 23;14:183. https://doi.org/10.3389/fnins.2020.00183.
• Oane I, Barborica A, Chetan F, Donos C, Maliia MD, Arbune AA, Daneasa A, Pistol C, Nica AE, Bajenaru OA, Mindruta I. Cingulate cortex function and multi-modal connectivity mapped using intracranial stimulation. Neuroimage. 2020 Oct 15;220:117059. https://doi.org/10.1016/j.neuroimage.2020.117059.
• Pistol C, Daneasa A, Ciurea J, Rasina A, Barborica A, Oane I, Mindruta I. Accuracy and Safety of Customized Stereotactic Fixtures for Stereoelectroencephalography in Pediatric Patients. Stereotact Funct Neurosurg. 2020 Nov 23:1-8. https://doi.org/10.1159/000510063. Epub ahead of print. PMID: 33227801.
• Bratu F-I, Oane I, Barborica A, Donos C, Pistol C, Daneasa A, Lentoiu C, Mindruta I. Network of autoscopic hallucinations elicited by intracerebral stimulations of periventricular nodular heterotopia: an SEEG study. Cortex 2021 - Under review.

Conferences:

2018

• Donos C, Maliia MD, Popa I, Arbune A, Mindruta I, Barborica A. Neurophysiology of Cognition: Insight from invasive recordings on epileptic patients. Consciousness, Free Will and Sense of Agency, 25-27 Sept. 2018, St. Hilda's College, Oxford
• Popa I, Maliia MD, Donos C, Arbune A, Mindruta I, Barborica A. Consciousness and Epileptic Seizures: An Epileptologist Perspective. Consciousness, Free Will and Sense of Agency, 25-27 Sept. 2018, St. Hilda's College, Oxford
• Popa I, Mindruta I, Barborica A, Maliia MD, Donos C, Daneasa A, Arbune A, Ciurea J. Cingulate cortex involvement in frontal lobe epilepsy - exploration using Stereoelectroencephalography (SEEG). 10th National Conference of the Romanian Society of Electrodiagnostic Neurophysiology (ASNER CN 2018), 26-28 Oct., Bucharest, Romania
• Mindruta I, Ciurea J, Popa I, Barborica A, Donos C, Maliia MD, Arbune A, Rasina A. Cingulate cortex involvement in frontal lobe epilepsy- exploration using Stereo-encephalography (SEEG). Congress of the European Society for Stereotactic and Functional Neurosurgery (ESSFN 2018), 26-29 Sept., Edinburgh, Scotland
• Popa I,   Barborica A, Scholly J, Donos C, Bartolomei F, Lagarde S, Hirsch H, Hirsch MPV, Maliia MD, Arbune A, Daneasa A, Ciurea J,   Bajenaru OA, Mindruta I. Human brain networks underlying illusory own body perceptions during high frequency stimulations of the cingulate gyrus - an SEEG study. 1st International Conference on Neuroscience, Neuroinformatics, Neurotechnology and Neuro-Psycho- Pharmacology 2018, 15-18 Nov., Bucharest, Romania
• Mindruta I, Barborica A, Donos C, Pistol C, Popa I, Daneasa A, Bajenaru OA. Intracerebral high frequency stimulation for the mapping of brain functions and connectivity. 1st International Conference on Neuroscience, Neuroinformatics, Neurotechnology and Neuro-Psycho- Pharmacology 2018, 15-18 Nov., Bucharest, Romania
• Maliia MD , Popa I, Donos C, Barborica A, Pistol C,  Daneasa A, Arbune A, Ciurea J, Mindruta I. Insular epilepsy. 10th National Conference of the Romanian Society of Electrodiagnostic Neurophysiology (ASNER CN 2018), 26-28 Oct 2018, Bucharest, Romania
• Maliia MD , Popa I, Donos C, Barborica A, Mindruta I. Electroclinical correlations 10th National Conference of the Romanian Society of Electrodiagnostic Neurophysiology (ASNER CN 2018), 26-28 Oct. 2018, Bucharest, Romania
• Mindruta I, Popa I, Ciurea J, Maliia MD Practice protocols for epilepsy surgery 26th Conference of Romanian Society Against Epilepsy (SRIE), 4-6 Oct 2018, Cluj, Romania Maliia MD , Popa I, Donos C, Barborica A, Mindruta I. EEG graphoelements 26th Conference of Romanian Society Against Epilepsy (SRIE), 4-6 Oct 2018, Cluj, Romania
• Maliia MD , Popa I, Mindruta I. Seizures’ classification 26th Conference of Romanian Society Against Epilepsy (SRIE), 4-6 Oct 2018, Cluj, Romania
• Maliia MD, Ciurea J,  Popa I, Mindruta I Hippocampal sclerosis 26th Conference of Romanian Society Against Epilepsy (SRIE), 4-6 Oct 2018, Cluj, Romania
• Maliia MD Usual EEG montages-when and why 9th Summer School of the Romanian Society of Electrodiagnostic Neurophysiology ASNER SDV2018 , 13-15 July 2018, Eforie Nord, Romania
• Maliia MD , Popa I, Arbune A, Mindruta I. Advanced EEG workshop -  Case presentations 9th Summer School of the Romanian Society of Electrodiagnostic Neurophysiology ASNER SDV2018 , 13-15 July 2018, Eforie Nord, Romania
• Alexandru I. Berceanu, Constantin A.D. Pistol, Claudiu Papasteri, Alexandra Sofonea, Romina Sehlanec, Catalina Poalelungi, Miralena I. Tomescu, Razvan I. Vasilescu, Ioana R. Podina, Catalin Nedelcea, Horea Murgu, Adrian I. Titieni, Andrei Barborica, Ioana Mandruta, Robert C. Froemke, Ioana Carcea. Imitation Behavior in Stress Management and Prosocial Attitudes - Neural and Endocrine Mechanisms -.  9th Annual Meeting of the Society for Social Neuroscience (S4SN 2018), 2 Nov., San Diego, California, USA.
• Popa I, Barborica A, Maliia MD, Donos C, Arbune A, Daneasa A, Ciurea J, Mindruta I. Resting state connectivity changes of normal brain structures due to AED modulation: an SEEG study. American Epilepsy Society Annual Meeting 2018 (AES 2018), 30 Nov.- 4 Dec., New Orleans, USA
• Maliia MD, Donos C, Barborica A, Popa I, Ciurea J, Arbune A, Mindruta I. Resting state networks deactivation in focal epilepsy. American Epilepsy Society Annual Meeting 2018 (AES 2018), 30 Nov.- 4 Dec., New Orleans, USA
• Arbune A, Mindruta I, Popa I, Maliia MD, Daneasa A, Ciurea J, Donos C, Bajenaru OA, Barborica A. Lobar connectivity during wakefulness and sleep studied through single pulse electrical stimulation in patients with focal epilepsy. American Epilepsy Society Annual Meeting 2018 (AES 2018), 30 Nov.- 4 Dec., New Orleans, USA
• Arbune A. A., Beniczky S., Popa I., Ciurea J., Bajenaru O. A., Barborica A., Mindruta I. Sleep-wakefulness connectivity variation in children with predominantly nocturnal focal seizures. 13th European Congress on Epileptology, 26-30th August 2018, Vienna, Austria
• Arbune A. A., Popa I., Maliia M.D., Daneasa A., Mindruta I. EEG - How long should we record? 9th Summer School of the Romanian Society of Electrodiagnostic Neurophysiology ASNER SDV2018 , 13-15 July 2018, Eforie Nord, Romania
• Daneasa A., Arbune A. A., Popa I., Maliia M.D.,  Mindruta I. Lateralization and localization in epilepsy. 9th Summer School of the Romanian Society of Electrodiagnostic Neurophysiology ASNER SDV2018 , 13-15 July 2018, Eforie Nord, Romania
• Arbune A. A., Barborica A., Mindruta I., Popa I., Maliia M.D., Daneasa A., Ciurea J., Rasina A., Donos C., Bajenaru O. A. Brain connectivity during wakefulness and sleep studied through direct electrical stimulation in patients with focal epilepsy. 1st International Conference on Neuroscience, Neuroinformatics, Neurotechnology and NeuroPsycho- Pharmacology, 15-17th November 2018, Bucharest, Romania

2019

 

• Irina Popa. Human brain networks underlying illusory own body perceptions during high frequency stimulations of the cingulate gyrus – An SEEG study. VERE Meeting, February 2019, Barcelona, Spain.
• Constantin Augustin-Dan Pistol, Claudiu Papasteri, Alexandra Sofonea, Romina Boldasu, Catalina Poalelungi, Miralena I. Tomescu, Adrian Titieni, Horea Murgu, Ioana Podina, Dragos Cirneci, Catalin Nedelcea, Irina Popa, Mihai-Dragos Maliia, Ioana Mindruta, Andrei Barborica, Alexandru Berceanu, Robert C. Froemke and Ioana Carcea, Neurophysiological Signatures for Imitation-Induced Social Emotional Regulation - The Future of Neuroscience, Attachment and Mentalizing: from research to clinical practice, 18-19 May 2019, UCL - London's Global University, London, England
• Cristian Donos. Inferring structural-effective connectivity distribution priors for a Bayesian framework from probabilistic tractography and intracranial electrical stimulation. European Conference on Clinical Neuroimaging , 20-21 May 2019 , Brussels, Belgium.
• Irina Popa, Andrei Barborica, Andrei Daneasa, Mihai Dragos Maliia, Anca Arbune, Cristian Donos, Ovidiu-Alexandru Bajenaru, Ioana Mindruta. Cingulate cortex involvement in frontal lobe epilepsy. National Meeting of the Romanian Society of Neurology, May 2019.
• Constantin Augustin-Dan Pistol, Claudiu Papasteri, Alexandra Sofonea, Romina Boldasu, Catalina Poalelungi, Miralena I. Tomescu, Adrian Titieni, Horea Murgu, Ioana Podina, Dragos Cirneci, Catalin Nedelcea, Irina Popa, Mihai-Dragos Maliia, Ioana Mindruta, Andrei Barborica, Alexandru Berceanu, Robert C. Froemke and Ioana Carcea, Neurophysiological Signatures for Imitation-Induced Social Buffering of Stress – The Organization for Human Brain Mapping (OHBM 2019), 9-13 June 2019, Rome, Italy
• Andrei Barborica. Brain networks activated while performing high-frequency intracranial stimulation for functional cortical mapping. 17th European Congress of Clinical Neurophysiology (ECCN 2019), 5-8 June 2019, Warsaw, Poland.- Oral Presentation
• Ioana Mindruta. Networks associated with clinical responses evoked by high-frequency intracranial stimulation. 17th European Congress of Clinical Neurophysiology (ECCN 2019), 5-8 June 2019, Warsaw, Poland.- Oral Presentation
• Irina Popa. Networks of ictal symptoms evoked by intracranial stimulation in patients with drug-resistant epilepsy explored through stereo-EEG method. 17th European Congress of Clinical Neurophysiology (ECCN 2019), 5-8 June 2019, Warsaw, Poland.- Oral Presentation
• Ioana Mindruta, Irina Popa, Andrei Daneasa, Cristian Donos, Felicia Mihai, Jean Ciurea, Andrei Barborica. Networks associated with clinical responses evoked by high-frequency intracranial stimulation. 17th European Congress of Clinical Neurophysiology (ECCN 2019), 5-8 June 2019, Warsaw, Poland.
• Andrei Daneasa, Andrei Barborica, Irina Popa, Mihai Maliia, Anca Arbune, Cristian Donos, Jan Ciurea, Ovidiu Bajenaru, Ioana Mindruta. Sleep stage dependent functional connectivity in SEEG. 17th European Congress of Clinical Neurophysiology (ECCN 2019), 5-8 June 2019, Warsaw, Poland.
• Andrei Barborica, Ioana Mindruta, Cristian Donos, Irina Popa, Felicia Mihai, Mihai Maliia, Andrei Daneasa, Anca Arbune, Constantin Pistol. Brain networks activated while performing high-frequency intracranial stimulation for functional cortical mapping. . 17th European Congress of Clinical Neurophysiology (ECCN 2019), 5-8 June 2019, Warsaw, Poland.
• Anca Adriana Arbune, Ioana Mindruta, Andrei Daneasa, Mihai Maliia, Irina Popa, Jean Ciurea, Cristian Donos, Ovidiu Alexandru Bajenaru, Andrei Barborica. Temporal lobe connectivity changes during wakefulness and sleep studied through single pulse electrical stimulation. 17th European Congress of Clinical Neurophysiology (ECCN 2019), 5-8 June 2019, Warsaw, Poland.
• Irina Popa, Ioana Mindruta. VideoEEG monitoring in cases with palliative treatment indication: VNS, DBS. ASNER Summer School, July 2019, Bucharest, Romania.
• Irina Oane, Ioana Mindruta. Antiepileptic drugs or surgery. East European Course of Epilepsy & SRIE epilepsy summer School, July 2019, Sucevita, Romania.

2020

 

• Ioana Mindruta, Irina Oane, Andrei Daneasa, Cristian Donos, Sergiu Stoica, Georgian Ciobotaru, Jean Ciurea, Andrei Barborica "Defining success in epilepsy surgery", Online National Conference of the Romanian League against Epilepsy, 4-7 November 2020. https://ilae-romania.ro/conferinta-srie-editia-a-xxvii-3/
• Camelia Lentoiu, Irina Oane, Andrei Barborica, Cristian Donos, Andrei Daneasa, Flavius I. Bratu, Ioana Mindruta. "Parietal lobe seizure: a combined scalp-intracranial electrode study", Online National Conference of the Romanian League against Epilepsy, 4-7 November 2020. https://ilae-romania.ro/conferinta-srie-editia-a-xxvii-3/
• Ionut-Flavius Bratu, Camelia Lentoiu, Tudor Cornel, Aura Dabu, Irina Oane, Andrei Daneasa, Sergiu Stoica, Georgian Ciobotaru, Andrei Barborica, Ioana Mindruta. "Anterior, middle and posterior insular cortex - an archipelago to be discovered: a scalp EEG-SEEG study", Online National Conference of the Romanian League against Epilepsy, 4-7 November 2020. https://ilae-romania.ro/conferinta-srie-editia-a-xxvii-3/
• Andrei Daneasa, Georgian Ciobotaru, Sergiu Stoica, Ioana Mindruta "PVNH - periventricular nodular heterotopia - case presentation", online, National Conference of the Romanian League against Epilepsy, 4-7 November 2020. https://ilae-romania.ro/conferinta-srie-editia-a-xxvii-3/
• Ioana Mindruta "Sleep-wake disorders and epilepsy", Online National Conference of the Romanian Neurology Society 17-19 november 2020. https://www.neurology.ro/images/stories/uploads/2020/program_congres_fara_curs.pdf
• Irina Oane, Ioana Mindruta "Epilepsy surgery in eloquent cortex - case presentation" 7th Tagliacozzo International Course on Drug Resistant Epilepsies - Virtual Event, 23-25 September 2020. http://www.epilepsytagliacozzo.com/
• Ioana Mîndruta, Andrei Barborica, Cristian Donos, Mihai Malîia, Irina Oane, Anca Arbune "Signal analysis methods to delineate the seizure onset zone" MEL2020 - Online Conference of the Hungarian Epilepsy League 29-30 october 2020. https://mel2020.hu/program.php

 

Open Source Software  PyEpi - Python pipeline for brain segmentation and tractography (http://github.com/cristidonos/pyepi)

Effective connectivity during Single Pulse Electrical Stimulation (SPES). Report generated with PyEpi: www.donos.ro/epiloc/pyepi_report.html Activation/Deactivation of functional network associated with complex somatosensitive symptoms evoked by high-frequency (50Hz) electrical stimulation.