Studying Cognitive Activity at several LEvels with Simultaneous depth and surface recordings

Grant COFUND-FLAGERA II-SCALES 15/2018

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Papers:

Malîia M-D, Donos C, Barborica A, Popa I, Ciurea J, Cinatti S, Mîndruta I (2018): Functional mapping and effective connectivity of the human operculum. Cortex 109:303-321. https://doi.org/10.1016/j.cortex.2018.08.024 Available at: http://www.sciencedirect.com/science/article/pii/S0010945218302764
Popa I, Barborica A, Scholly J, Donos C, Bartolomei F, Lagarde S, Hirsch E Valenti-Hirsch MP, Maliia MD, Arbune AA, Daneasa A, Ciurea J, Bajenaru OA, Mindruta I. Illusory own body perceptions mapped in the cingulate cortex—An intracranial stimulation study. Hum Brain Mapp. 2019;40:2813–26. https://doi.org/10.1002/hbm.24563.
Arbune AA, Popa I, Mindruta I, Beniczky S, Donos C, Daneasa A, Malîia MD, Bajenaru OA, Ciurea J, Barborica A. Sleep modulates effective connectivity: a study using intracranial stimulation and recording. Clin Neurophysiol. 2020 Feb;131(2):529-541. https://doi.org/10.1016/j.clinph.2019.09.010. Available at: https://www.sciencedirect.com/science/article/abs/pii/S1388245719312398
Donos C, Mindruta I, Barborica A. Unsupervised Detection of High-Frequency Oscillations Using Time-Frequency Maps and Computer Vision. Front Neurosci. 2020 Mar 23;14:183. https://doi.org/10.3389/fnins.2020.00183.
Oane I, Barborica A, Chetan F, Donos C, Maliia MD, Arbune AA, Daneasa A, Pistol C, Nica AE, Bajenaru OA, Mindruta I. Cingulate cortex function and multi-modal connectivity mapped using intracranial stimulation. Neuroimage. 2020 Oct 15;220:117059. https://doi.org/10.1016/j.neuroimage.2020.117059.
Pistol C, Daneasa A, Ciurea J, Rasina A, Barborica A, Oane I, Mindruta I. Accuracy and Safety of Customized Stereotactic Fixtures for Stereoelectroencephalography in Pediatric Patients. Stereotact Funct Neurosurg. 2021;99(1):17-24. https://doi.org/10.1159/000510063.. Epub 2020 Nov 23.
Andrei Barborica, Ioana Mindruta, Laurent Sheybani, Laurent Spinelli, Irina Oane, Constantin Pistol, Cristian Donos, Víctor J López-Madrona, Serge Vulliemoz, Christian-George Bénar. Extracting seizure onset from surface EEG with Independent Component Analysis: insights from simultaneous scalp and intracerebral EEG, Submitted to Neuroimage: Clinical, Jan 2021.

Conferences:

2018

Donos C, Maliia MD, Popa I, Arbune A, Mindruta I, Barborica A. Neurophysiology of Cognition: Insight from invasive recordings on epileptic patients. Consciousness, Free Will and Sense of Agency, 25-27 Sept. 2018, St. Hilda's College, Oxford
Popa I, Maliia MD, Donos C, Arbune A, Mindruta I, Barborica A. Consciousness and Epileptic Seizures: An Epileptologist Perspective. Consciousness, Free Will and Sense of Agency, 25-27 Sept. 2018, St. Hilda's College, Oxford
Popa I, Mindruta I, Barborica A, Maliia MD, Donos C, Daneasa A, Arbune A, Ciurea J. Cingulate cortex involvement in frontal lobe epilepsy - exploration using Stereoelectroencephalography (SEEG). 10th National Conference of the Romanian Society of Electrodiagnostic Neurophysiology (ASNER CN 2018), 26-28 Oct., Bucharest, Romania
Mindruta I, Ciurea J, Popa I, Barborica A, Donos C, Maliia MD, Arbune A, Rasina A. Cingulate cortex involvement in frontal lobe epilepsy- exploration using Stereo-encephalography (SEEG). Congress of the European Society for Stereotactic and Functional Neurosurgery (ESSFN 2018), 26-29 Sept., Edinburgh, Scotland
Popa I, Barborica A, Scholly J, Donos C, Bartolomei F, Lagarde S, Hirsch H, Hirsch MPV, Maliia MD, Arbune A, Daneasa A, Ciurea J, Bajenaru OA, Mindruta I. Human brain networks underlying illusory own body perceptions during high frequency stimulations of the cingulate gyrus - an SEEG study. 1st International Conference on Neuroscience, Neuroinformatics, Neurotechnology and Neuro-Psycho- Pharmacology 2018, 15-18 Nov., Bucharest, Romania
Mindruta I, Barborica A, Donos C, Pistol C, Popa I, Daneasa A, Bajenaru OA. Intracerebral high frequency stimulation for the mapping of brain functions and connectivity. 1st International Conference on Neuroscience, Neuroinformatics, Neurotechnology and Neuro-Psycho- Pharmacology 2018, 15-18 Nov., Bucharest, Romania
Maliia MD , Popa I, Donos C, Barborica A, Pistol C, Daneasa A, Arbune A, Ciurea J, Mindruta I. Insular epilepsy. 10th National Conference of the Romanian Society of Electrodiagnostic Neurophysiology (ASNER CN 2018), 26-28 Oct 2018, Bucharest, Romania
Maliia MD , Popa I, Donos C, Barborica A, Mindruta I. Electroclinical correlations 10th National Conference of the Romanian Society of Electrodiagnostic Neurophysiology (ASNER CN 2018), 26-28 Oct. 2018, Bucharest, Romania
Mindruta I, Popa I, Ciurea J, Maliia MD Practice protocols for epilepsy surgery 26th Conference of Romanian Society Against Epilepsy (SRIE), 4-6 Oct 2018, Cluj, Romania Maliia MD , Popa I, Donos C, Barborica A, Mindruta I. EEG graphoelements 26th Conference of Romanian Society Against Epilepsy (SRIE), 4-6 Oct 2018, Cluj, Romania
Maliia MD , Popa I, Mindruta I. Seizures’ classification 26th Conference of Romanian Society Against Epilepsy (SRIE), 4-6 Oct 2018, Cluj, Romania
Maliia MD, Ciurea J, Popa I, Mindruta I Hippocampal sclerosis 26th Conference of Romanian Society Against Epilepsy (SRIE), 4-6 Oct 2018, Cluj, Romania
Maliia MD Usual EEG montages-when and why 9th Summer School of the Romanian Society of Electrodiagnostic Neurophysiology ASNER SDV2018 , 13-15 July 2018, Eforie Nord, Romania
Maliia MD , Popa I, Arbune A, Mindruta I. Advanced EEG workshop - Case presentations 9th Summer School of the Romanian Society of Electrodiagnostic Neurophysiology ASNER SDV2018 , 13-15 July 2018, Eforie Nord, Romania
Alexandru I. Berceanu, Constantin A.D. Pistol, Claudiu Papasteri, Alexandra Sofonea, Romina Sehlanec, Catalina Poalelungi, Miralena I. Tomescu, Razvan I. Vasilescu, Ioana R. Podina, Catalin Nedelcea, Horea Murgu, Adrian I. Titieni, Andrei Barborica, Ioana Mandruta, Robert C. Froemke, Ioana Carcea. Imitation Behavior in Stress Management and Prosocial Attitudes - Neural and Endocrine Mechanisms -. 9th Annual Meeting of the Society for Social Neuroscience (S4SN 2018), 2 Nov., San Diego, California, USA.
Popa I, Barborica A, Maliia MD, Donos C, Arbune A, Daneasa A, Ciurea J, Mindruta I. Resting state connectivity changes of normal brain structures due to AED modulation: an SEEG study. American Epilepsy Society Annual Meeting 2018 (AES 2018), 30 Nov.- 4 Dec., New Orleans, USA
Maliia MD, Donos C, Barborica A, Popa I, Ciurea J, Arbune A, Mindruta I. Resting state networks deactivation in focal epilepsy. American Epilepsy Society Annual Meeting 2018 (AES 2018), 30 Nov.- 4 Dec., New Orleans, USA
Arbune A, Mindruta I, Popa I, Maliia MD, Daneasa A, Ciurea J, Donos C, Bajenaru OA, Barborica A. Lobar connectivity during wakefulness and sleep studied through single pulse electrical stimulation in patients with focal epilepsy. American Epilepsy Society Annual Meeting 2018 (AES 2018), 30 Nov.- 4 Dec., New Orleans, USA
Arbune A. A., Beniczky S., Popa I., Ciurea J., Bajenaru O. A., Barborica A., Mindruta I. Sleep-wakefulness connectivity variation in children with predominantly nocturnal focal seizures. 13th European Congress on Epileptology, 26-30th August 2018, Vienna, Austria
Arbune A. A., Popa I., Maliia M.D., Daneasa A., Mindruta I. EEG - How long should we record? 9th Summer School of the Romanian Society of Electrodiagnostic Neurophysiology ASNER SDV2018 , 13-15 July 2018, Eforie Nord, Romania
Daneasa A., Arbune A. A., Popa I., Maliia M.D., Mindruta I. Lateralization and localization in epilepsy. 9th Summer School of the Romanian Society of Electrodiagnostic Neurophysiology ASNER SDV2018 , 13-15 July 2018, Eforie Nord, Romania
Arbune A. A., Barborica A., Mindruta I., Popa I., Maliia M.D., Daneasa A., Ciurea J., Rasina A., Donos C., Bajenaru O. A. Brain connectivity during wakefulness and sleep studied through direct electrical stimulation in patients with focal epilepsy. 1st International Conference on Neuroscience, Neuroinformatics, Neurotechnology and NeuroPsycho- Pharmacology, 15-17th November 2018, Bucharest, Romania

2019

Irina Popa. Human brain networks underlying illusory own body perceptions during high frequency stimulations of the cingulate gyrus – An SEEG study. VERE Meeting, February 2019, Barcelona, Spain.
Constantin Augustin-Dan Pistol, Claudiu Papasteri, Alexandra Sofonea, Romina Boldasu, Catalina Poalelungi, Miralena I. Tomescu, Adrian Titieni, Horea Murgu, Ioana Podina, Dragos Cirneci, Catalin Nedelcea, Irina Popa, Mihai-Dragos Maliia, Ioana Mindruta, Andrei Barborica, Alexandru Berceanu, Robert C. Froemke and Ioana Carcea, Neurophysiological Signatures for Imitation-Induced Social Emotional Regulation - The Future of Neuroscience, Attachment and Mentalizing: from research to clinical practice, 18-19 May 2019, UCL - London's Global University, London, England
Cristian Donos. Inferring structural-effective connectivity distribution priors for a Bayesian framework from probabilistic tractography and intracranial electrical stimulation. European Conference on Clinical Neuroimaging , 20-21 May 2019 , Brussels, Belgium.
Irina Popa, Andrei Barborica, Andrei Daneasa, Mihai Dragos Maliia, Anca Arbune, Cristian Donos, Ovidiu-Alexandru Bajenaru, Ioana Mindruta. Cingulate cortex involvement in frontal lobe epilepsy. National Meeting of the Romanian Society of Neurology, May 2019.
Constantin Augustin-Dan Pistol, Claudiu Papasteri, Alexandra Sofonea, Romina Boldasu, Catalina Poalelungi, Miralena I. Tomescu, Adrian Titieni, Horea Murgu, Ioana Podina, Dragos Cirneci, Catalin Nedelcea, Irina Popa, Mihai-Dragos Maliia, Ioana Mindruta, Andrei Barborica, Alexandru Berceanu, Robert C. Froemke and Ioana Carcea, Neurophysiological Signatures for Imitation-Induced Social Buffering of Stress – The Organization for Human Brain Mapping (OHBM 2019), 9-13 June 2019, Rome, Italy
Andrei Barborica. Brain networks activated while performing high-frequency intracranial stimulation for functional cortical mapping. 17th European Congress of Clinical Neurophysiology (ECCN 2019), 5-8 June 2019, Warsaw, Poland.- Oral Presentation
Ioana Mindruta. Networks associated with clinical responses evoked by high-frequency intracranial stimulation. 17th European Congress of Clinical Neurophysiology (ECCN 2019), 5-8 June 2019, Warsaw, Poland.- Oral Presentation
Irina Popa. Networks of ictal symptoms evoked by intracranial stimulation in patients with drug-resistant epilepsy explored through stereo-EEG method. 17th European Congress of Clinical Neurophysiology (ECCN 2019), 5-8 June 2019, Warsaw, Poland.- Oral Presentation
Ioana Mindruta, Irina Popa, Andrei Daneasa, Cristian Donos, Felicia Mihai, Jean Ciurea, Andrei Barborica. Networks associated with clinical responses evoked by high-frequency intracranial stimulation. 17th European Congress of Clinical Neurophysiology (ECCN 2019), 5-8 June 2019, Warsaw, Poland.
Andrei Daneasa, Andrei Barborica, Irina Popa, Mihai Maliia, Anca Arbune, Cristian Donos, Jan Ciurea, Ovidiu Bajenaru, Ioana Mindruta. Sleep stage dependent functional connectivity in SEEG. 17th European Congress of Clinical Neurophysiology (ECCN 2019), 5-8 June 2019, Warsaw, Poland.
Andrei Barborica, Ioana Mindruta, Cristian Donos, Irina Popa, Felicia Mihai, Mihai Maliia, Andrei Daneasa, Anca Arbune, Constantin Pistol. Brain networks activated while performing high-frequency intracranial stimulation for functional cortical mapping. . 17th European Congress of Clinical Neurophysiology (ECCN 2019), 5-8 June 2019, Warsaw, Poland.
Anca Adriana Arbune, Ioana Mindruta, Andrei Daneasa, Mihai Maliia, Irina Popa, Jean Ciurea, Cristian Donos, Ovidiu Alexandru Bajenaru, Andrei Barborica. Temporal lobe connectivity changes during wakefulness and sleep studied through single pulse electrical stimulation. 17th European Congress of Clinical Neurophysiology (ECCN 2019), 5-8 June 2019, Warsaw, Poland.
Irina Popa, Ioana Mindruta. VideoEEG monitoring in cases with palliative treatment indication: VNS, DBS. ASNER Summer School, July 2019, Bucharest, Romania.
Irina Oane, Ioana Mindruta. Antiepileptic drugs or surgery. East European Course of Epilepsy & SRIE epilepsy summer School, July 2019, Sucevita, Romania.

2020

Ioana Mindruta, Irina Oane, Andrei Daneasa, Cristian Donos, Sergiu Stoica, Georgian Ciobotaru, Jean Ciurea, Andrei Barborica "Defining success in epilepsy surgery", Online National Conference of the Romanian League against Epilepsy, 4-7 November 2020. https://ilae-romania.ro/conferinta-srie-editia-a-xxvii-3/
Camelia Lentoiu, Irina Oane, Andrei Barborica, Cristian Donos, Andrei Daneasa, Flavius I. Bratu, Ioana Mindruta. "Parietal lobe seizure: a combined scalp-intracranial electrode study", Online National Conference of the Romanian League against Epilepsy, 4-7 November 2020. https://ilae-romania.ro/conferinta-srie-editia-a-xxvii-3/
Ionut-Flavius Bratu, Camelia Lentoiu, Tudor Cornel, Aura Dabu, Irina Oane, Andrei Daneasa, Sergiu Stoica, Georgian Ciobotaru, Andrei Barborica, Ioana Mindruta. "Anterior, middle and posterior insular cortex - an archipelago to be discovered: a scalp EEG-SEEG study", Online National Conference of the Romanian League against Epilepsy, 4-7 November 2020. https://ilae-romania.ro/conferinta-srie-editia-a-xxvii-3/
Andrei Daneasa, Georgian Ciobotaru, Sergiu Stoica, Ioana Mindruta "PVNH - periventricular nodular heterotopia - case presentation", online, National Conference of the Romanian League against Epilepsy, 4-7 November 2020. https://ilae-romania.ro/conferinta-srie-editia-a-xxvii-3/
Ioana Mindruta "Sleep-wake disorders and epilepsy", Online National Conference of the Romanian Neurology Society 17-19 november 2020. https://www.neurology.ro/images/stories/uploads/2020/program_congres_fara_curs.pdf
Irina Oane, Ioana Mindruta "Epilepsy surgery in eloquent cortex - case presentation" 7th Tagliacozzo International Course on Drug Resistant Epilepsies - Virtual Event, 23-25 September 2020. http://www.epilepsytagliacozzo.com/
Ioana MiÌ‚ndruta, Andrei Barborica, Cristian Donos, Mihai MaliÌ‚ia, Irina Oane, Anca Arbune "Signal analysis methods to delineate the seizure onset zone" MEL2020 - Online Conference of the Hungarian Epilepsy League 29-30 october 2020. https://mel2020.hu/program.php

2021

Andrei Barborica, Ioana Mindruta, Christian G. Benar, Serge Vulliemoz, Irina Oane, Felicia Mihai, Cristian Donos, Constantin Pistol. What Scalp Recordings Tell Us About Intracranial Stimulations? A Simultaneous Scalp-SEEG Study, American Epilepsy Society (AES) Anual Meeting 2021, Dec 3-7, Chicago, USA.
Ioana Mindruta, Irina Oane, Flavius Bratu, Camelia Lentoiu, Felicia Mihai, Cristian Donos, Andrei Barborica. Insular-Cingulate Resting State and Symptom Related Connectivity Interplay in Patients with Drug-Resistant Epilepsy, American Epilepsy Society (AES) Anual Meeting 2021, Dec 3-7, Chicago, USA.
Sandra Munteanu, Andrei Barborica, Irina Oane, Ioana Mindruta. Concomitant recordings scalp - intracranial SEEG in insular lobe seizures. 12th Summer School of the Romanian Society of Electrodiagnostic Neurophysiology (ASNER), 9-10 July 2021, Eforie, Romania.
Andrei Daneasa, Irina Oane, Andrei Barborica, Cristian Donos, Constantin Pistol, Ioana Mindruta. The contribution of EEG source imaging in the diagnosis of epilepsy. 12th Summer School of the Romanian Society of Electrodiagnostic Neurophysiology (ASNER), 9-10 July 2021, Eforie, Romania.
Irina Oane, Andrei Barborica, Cristian Donos, Constantin Pistol, Andrei Daneasa, Camelia Lentoiu, Flavius Bratu, Ioana Mindruta. Reflex seizures and the brain networks involved. 12th Summer School of the Romanian Society of Electrodiagnostic Neurophysiology (ASNER), 9-10 July 2021, Eforie, Romania.

Open Source Software

PyEpi - Python pipeline for brain segmentation and tractography (http://github.com/cristidonos/pyepi)
Effective connectivity report generated with PyEpi: www.donos.ro/epiloc/pyepi_report.html